Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405980 | 0.82 | KDM4E (0.50) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL35762 | 0.82 | KDM4E (0.50) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27657491 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27690512 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27310412 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28283656 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27296965 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL776642 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5488308 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL28155260 | 0.80 | KDM4E (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070039-A2 | Polymerization catalyst and process for polymerizing alpha-olefins | PHILLIPS PETROLEUM COMPANY (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4243552-A | MAGNESIUM CHLORIDE OR MANGANESE CHLORIDE AND ADJUVANT | PHILLIPS PETROLEUM COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| EP-0012397-A1 | Polymerization catalyst and process for polymerizing alpha-olefins | PHILLIPS PETROLEUM COMPANY (US) | 1980-06-25 | — | — | EP | disclosed |