SCHEMBL11200330

SCHEMBL11200330

Cc1ccc(C/C=C/CO)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.42
AGXT P21549 2/20 0.41
IDO1 P14902 3/20 0.41
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ACHE P22303 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
POLB P06746 2/20 0.34
GAA P10253 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11200333 1.00 MAOB (0.42) MAOBAGXTIDO1CYP1A2CYP2A6
SCHEMBL11400752 0.88 MAOB (0.52) MAOBAGXTIDO1CYP1A2CYP2A6
SCHEMBL27881548 0.82 MAOB (0.42) MAOBIDO1CYP2A6TAAR1ALDH1A1
SCHEMBL6683227 0.79 MAOB (0.44) MAOBAGXTIDO1CYP1A2CYP2A6
SCHEMBL28478078 0.79 AGXT (0.43) MAOBAGXTIDO1CYP1A2CYP2A6
SCHEMBL1051791 0.79 MAOB (0.44) MAOBAGXTIDO1CYP1A2CYP2A6
SCHEMBL9663380 0.78 BCHE (0.50) CYP1A2ACHEGAAMEN1ALDH1A1
SCHEMBL28760384 0.77 MAOB (0.42) MAOBIDO1CYP2A6TAAR1MEN1
SCHEMBL10805006 0.77 KCNH2 (0.45) MAOBAGXTIDO1CYP2A6TAAR1
SCHEMBL10805012 0.77 KCNH2 (0.45) MAOBAGXTIDO1CYP2A6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411912-A Insecticidal isovaleric acid esters ZOECON CORPORATION (US) 1983-10-25 US disclosed
US-4243819-A Substituted amino acids ZOECON CORPORATION (US) 1981-01-06 US disclosed