Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11185021 | 0.88 | POLB (0.54) | POLBMCHR1CNR1PTGS2DNMT3A | |
| SCHEMBL11438097 | 0.83 | MCHR1 (0.49) | POLBMCHR1CNR1PTGS2ALDH1A1 | |
| SCHEMBL11204199 | 0.83 | MCHR1 (0.54) | POLBMCHR1CNR1PTGS2CXCR3 | |
| SCHEMBL11188865 | 0.83 | POLB (0.56) | POLBMCHR1CNR1PTGS2LMNA | |
| SCHEMBL10356773 | 0.82 | MCHR1 (0.55) | POLBMCHR1CNR1PTGS2CXCR3 | |
| SCHEMBL11165965 | 0.82 | MCHR1 (0.55) | POLBMCHR1CNR1PTGS2CXCR3 | |
| SCHEMBL11165531 | 0.82 | MCHR1 (0.55) | POLBMCHR1CNR1PTGS2CXCR3 | |
| SCHEMBL11189302 | 0.81 | POLB (0.52) | POLBMCHR1CNR1PTGS2CYP2D6 | |
| SCHEMBL11441498 | 0.81 | MCHR1 (0.56) | POLBMCHR1CNR1CXCR3LMNA | |
| SCHEMBL11220179 | 0.80 | MCHR1 (0.54) | POLBMCHR1CNR1PTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |