SCHEMBL11200689

SCHEMBL11200689

O=C(Oc1cccc(O)c1)C(O)CO

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.54
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
POLB P06746 1/20 0.45
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
EGFR P00533 1/20 0.39
APP P05067 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
SERPINE1 P05121 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL3671325 0.84 CYP3A4 (0.44) CYP3A4ESR1ESR2ADRB2ADRB1
SCHEMBL688988 0.84 CYP3A4 (0.51) CYP3A4ESR1ESR2POLBMEN1
SCHEMBL27705567 0.84 CYP3A4 (0.51) CYP3A4ESR1ESR2POLBMEN1
SCHEMBL688921 0.82 CYP3A4 (0.61) CYP3A4ESR1ESR2POLBMEN1
SCHEMBL5198959 0.80 ATM (0.47) MEN1KMT2AADRB2ADRB1ADRB3
SCHEMBL10787310 0.79 CYP3A4 (0.62) CYP3A4ESR1ESR2POLBMEN1
SCHEMBL11198182 0.79 ELANE (0.40) ESR1ESR2MEN1KMT2A
SCHEMBL10720409 0.77 CYP3A4 (0.70) CYP3A4ESR1ESR2POLBMEN1
SCHEMBL27705573 0.77 CYP3A4 (0.54) CYP3A4ESR1ESR2POLBMEN1
SCHEMBL2742146 0.75 CYP3A4 (0.57) CYP3A4ESR1ESR2POLBCHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4390683-A Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-06-28 US disclosed
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed