Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782944 | 0.85 | GRM5 (0.35) | MAPKAPK2JAK3L3MBTL1POLBALDH1A1 | |
| SCHEMBL15751419 | 0.83 | GSK3B (0.37) | JAK3L3MBTL1POLBALDH1A1KDM4E | |
| SCHEMBL14684041 | 0.83 | GRM5 (0.34) | JAK3L3MBTL1POLBALDH1A1GRM5 | |
| SCHEMBL3403252 | 0.79 | KDM4E (0.37) | L3MBTL1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL18502143 | 0.78 | GRM5 (0.49) | MAPKAPK2ALDH1A1GRM5 | |
| SCHEMBL30112052 | 0.78 | HPGD (0.39) | JAK3ALDH1A1KDM4EGRM5HPGD | |
| SCHEMBL7422568 | 0.78 | HPGD (0.39) | JAK3ALDH1A1KDM4EGRM5HPGD | |
| SCHEMBL29361842 | 0.78 | SMN1; SMN2 (0.40) | JAK3POLBKDM4EGRM5KMT2A | |
| SCHEMBL2491805 | 0.78 | SMN1; SMN2 (0.40) | JAK3POLBKDM4EGRM5KMT2A | |
| SCHEMBL3460085 | 0.76 | SIRT3 (0.37) | JAK3POLBALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797000-A | Amidine compound or salt thereof | TAISHO PHARMACEUTICAL CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-102292826-A | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | — | 2011-12-21 | — | — | CN | disclosed |
| EP-0076085-A1 | Production of monoacylpyrazines | PHILIP MORRIS INCORPORATED (US) | 1983-04-06 | — | — | EP | disclosed |