Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30715302 | 0.89 | BRD4 (0.44) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26696495 | 0.89 | BRD4 (0.44) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26696471 | 0.89 | BRD4 (0.44) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL30715297 | 0.89 | BRD4 (0.44) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL30715296 | 0.89 | BRD4 (0.44) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL30714923 | 0.88 | BRD4 (0.47) | BRD4 | |
| SCHEMBL30715289 | 0.87 | BRD4 (0.43) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26696480 | 0.87 | BRD4 (0.43) | BRD4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7607390 | 0.86 | BRD4 (0.51) | BRD4P2RX7 | |
| SCHEMBL30715307 | 0.86 | BRD4 (0.42) | BRD4OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405357-A | Herbicidal 3-isoxazolidinones and hydroxamic acids | FMC CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |