Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | PPOX | P50336 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262239 | 0.90 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10692395 | 0.90 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11188320 | 0.89 | TDP1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10966622 | 0.89 | TDP1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10554944 | 0.89 | MEN1 (0.69) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11200532 | 0.89 | TDP1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11218119 | 0.88 | TDP1 (0.65) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11217304 | 0.87 | TDP1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10992161 | 0.87 | TDP1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11129230 | 0.86 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077961-A2 | Substituted 2-nitro-5-(4-trifluoromethyl-phenoxy) toluols, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | disclosed |