SCHEMBL11202171

SCHEMBL11202171

Cc1nc2ccc3nc(C)c(C)nc3c2nc1C

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.62
TDP1 Q9NUW8 1/20 0.41
GPR3 P46089 1/20 0.39
KDM4E B2RXH2 6/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.37
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
DHFR P00374 3/20 0.36
CYP1A2 P05177 3/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
NQO2 P16083 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
STAT3 P40763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9533409 0.85 MAPT (0.50) MAPTTDP1GPR3KDM4EALDH1A1
SCHEMBL12313653 0.82 MAPT (0.63) MAPTTDP1GPR3KDM4ESMN1; SMN2
SCHEMBL11203532 0.78 MAPT (0.44) MAPTTDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL10389791 0.78 MAPT (0.61) MAPTTDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL18083015 0.78 MAPT (1.00) MAPTKDM4EALDH1A1MAPK1RAB9A
SCHEMBL12964209 0.78 MAPT (0.70) MAPTKDM4EALDH1A1MAPK1RAB9A
SCHEMBL11204399 0.77 MAPT (0.43) MAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL18704721 0.77 MAPT (0.47) MAPTTDP1GPR3KDM4EALDH1A1
SCHEMBL15424563 0.77 PRMT5 (0.53) MAPTTDP1GPR3ALDH1A1MAPK1
SCHEMBL8604288 0.76 MAPT (0.52) MAPTGPR3KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed