Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206837 | 0.89 | AR (0.64) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL9622215 | 0.88 | AR (0.68) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL835740 | 0.88 | AR (0.68) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL11142368 | 0.88 | AR (0.56) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL6944506 | 0.87 | AR (0.63) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL11244221 | 0.87 | AR (0.63) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL11239936 | 0.86 | AR (0.48) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL24358686 | 0.85 | AR (0.80) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL24358738 | 0.85 | AR (0.80) | ARPGRCHRM1LMNAHIF1A | |
| SCHEMBL24358698 | 0.85 | AR (0.80) | ARPGRCHRM1LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034115-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| EP-0034115-A2 | Process for the preparation of 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-19 | — | — | EP | disclosed |