SCHEMBL1120426

SCHEMBL1120426

Cc1ccc(C2CO2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
ALOX12 P18054 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
MAOB P27338 7/20 0.42
CHRM2 P08172 2/20 0.39
CHRM4 P08173 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
CYP19A1 P11511 1/20 0.38
MAPT P10636 1/20 0.38
GSTO1 P78417 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6482473 1.00 TSHR (0.56) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL6135142 1.00 TSHR (0.56) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL10684124 0.97 TSHR (0.54) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL10684133 0.97 TSHR (0.54) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL12841102 0.93 TSHR (0.50) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL13839948 0.87 TSHR (0.45) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL46155 0.86 TSHR (0.72) TSHRCHRM2CHRM4CHRM1CHRM3
SCHEMBL10689902 0.84 CHRM2 (0.42) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL10688813 0.84 TSHR (0.42) TSHRALDH1A1LMNAALOX12SMN1; SMN2
SCHEMBL10688802 0.84 TSHR (0.42) TSHRALDH1A1LMNAALOX12SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118563343-A Hydroboration reaction method for electrochemical catalysis of epoxy compound 南京林业大学 2024-08-30 CN claimed
CN-115927276-B Halohydrin dehalogenase mutant and application thereof in synthesis of chiral oxazolidinone 中国科学院天津工业生物技术研究所 2024-08-27 CN claimed
CN-117126044-B Microwave-assisted synthesis method of methyl ketone compound 延边大学 2024-01-26 CN claimed
CN-117126044-A Microwave-assisted synthesis method of methyl ketone compound 延边大学 2023-11-28 CN claimed
CN-116444196-B Composite water reducing agent and application thereof 北京鼎瀚中航建设有限公司 2023-08-22 CN claimed
CN-116355106-B Preparation method of starch-based water reducer 北京慕湖外加剂有限公司 2023-08-08 CN claimed
CN-116444196-A Composite water reducing agent and application thereof 北京鼎瀚中航建设有限公司 2023-07-18 CN claimed
CN-116355106-A Preparation method of starch-based water reducer 北京慕湖外加剂有限公司 2023-06-30 CN claimed
EP-2683749-B1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS GRACE W R & CO (US) 2023-06-07 EP claimed
CN-115927276-A Halogen alcohol dehalogenase mutant and application thereof in synthesizing chiral oxazolidinone 中国科学院天津工业生物技术研究所 2023-04-07 CN claimed
US-9090720-B2 Aluminoxane catalyst activators containing carbocation agents, and use thereof in polyolefin catalysts ALBEMARLE CORPORATION (US) 2015-07-28 US claimed
EP-2683749-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS Albemarle Corporation (US) 2014-01-15 EP claimed
US-20130345376-A1 Aluminoxane Catalyst Activators Containing Carbocation Agents, and use thereof in Polyolefin Catalysts ALBEMARLE CORPORATION (US) 2013-12-26 US claimed
WO-2012122332-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS ALBEMARLE CORPORATION (US) 2012-09-13 WO claimed
US-20120184472-A1 COMBINATIONS OF PHOSPHORUS-CONTAINING COMPOUNDS FOR USE AS ANTI-WEAR ADDITIVES IN LUBRICANT COMPOSITION AFTON CHEMICAL CORPORATION (US) 2012-07-19 US claimed
EP-2298854-A1 Combinations of phosphorus-containing compounds for use as anti-wear additives in lubricant compositions Afton Chemical Corporation (US) 2011-03-23 EP claimed
US-20110046029-A1 Combinations of Phosphorus-Containing Compounds For Use As Anti-Wear Additives In Lubricant Compositions AFTON CHEMICAL CORPORATION 2011-02-24 US claimed
US-4511516-A ARYL-SUBSTITUTED 5-AZA-1-BORA-2,8-DIOXACYCLOOCTANE, OIL ADDITIVES UNION OIL COMPANY OF CALIFORNIA (US) 1985-04-16 US claimed
EP-0003835-B1 A HYDROXY-UREA, PROCESS FOR PRODUCING THE SAME AND A PROCESS FOR PRODUCING A PHENYL-SUBSTITUTED N-METHOXY-N-METHYL-UREA SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-02 EP claimed
EP-0003835-A1 A hydroxy-urea, process for producing the same and a process for producing a phenyl-substituted N-methoxy-N-methyl-urea SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-09-05 EP claimed