Methacrylic Acid

Methacrylic Acid

SCHEMBL11204307

C=C(C)C(=O)O.C=CC(=O)Oc1ccc(Br)c(Br)c1Br

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.36
THRB P10828 3/20 0.35
THRA P10827 1/20 0.35
NCEH1 Q6PIU2 4/20 0.32
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.31
CFD P00746 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30596831 0.89 TYMS (0.42) TYMSTHRBTHRANCEH1PKM
SCHEMBL331642 0.89 TYMS (0.42) TYMSTHRBTHRANCEH1PKM
SCHEMBL9857933 0.85 TYMS (0.38) TYMSTHRBTHRANCEH1PKM
Methacrylic Acid SCHEMBL8429014 0.84 ELANE (0.41) NCEH1KDM4EPKMCFDNPC1
Oxirane SCHEMBL2834269 0.82 TYMS (0.41) TYMSTHRBTHRANCEH1NPC1
SCHEMBL331217 0.79 ELANE (0.40) NCEH1KDM4EPKMCFDNPC1
SCHEMBL28086981 0.79 TYMS (0.33) TYMSTHRBTHRANCEH1
Methacrylic Acid SCHEMBL27633362 0.79 AKR1C3 (0.35) THRBKDM4EPKMMAPT
SCHEMBL6763818 0.77 MAPT (0.36) TYMSTHRBTHRANPC1MAPT
SCHEMBL9773754 0.77 TSHR (0.41) THRBTHRANCEH1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP disclosed