Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PRKCI | P41743 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203169 | 0.92 | P2RY12 (0.48) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11197747 | 0.90 | KDM4E (0.53) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11203359 | 0.90 | P2RY12 (0.47) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11199766 | 0.90 | PRKCI (0.53) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11197165 | 0.90 | P2RY12 (0.49) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11199721 | 0.89 | P2RY12 (0.50) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11203889 | 0.87 | MEN1 (0.46) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11206143 | 0.86 | KDM4E (0.49) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11205665 | 0.84 | KDM4E (0.44) | P2RY12KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11198078 | 0.83 | P2RY12 (0.48) | P2RY12KDM4EALDH1A1SMN1; SMN2TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |