Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15770439 | 0.82 | MCHR1 (0.52) | MCHR1KCNH2CYP3A4MEN1NPC1 | |
| SCHEMBL2953604 | 0.78 | MCHR1 (0.79) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL10785320 | 0.76 | RECQL (0.54) | MCHR1KCNH2CYP3A4NPC1RAB9A | |
| SCHEMBL12340340 | 0.76 | MCHR1 (0.81) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL2959141 | 0.76 | MCHR1 (0.78) | MCHR1KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2955403 | 0.75 | MCHR1 (0.77) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL319515 | 0.74 | RECQL (0.61) | NPC1RAB9A | |
| SCHEMBL29850579 | 0.74 | MCHR1 (0.47) | MCHR1KCNH2CYP3A4MEN1NPC1 | |
| SCHEMBL3917675 | 0.73 | SRD5A2 (0.56) | MCHR1KCNH2MEN1NPC1RAB9A | |
| SCHEMBL11194119 | 0.73 | NPC1 (0.49) | MCHR1CYP3A4MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4409234-A | Pyrazoloindazole derivatives and bronchodilating composition | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0023633-B1 | PYRAZOLOINDAZOLE DERIVATIVES AND PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-11-24 | — | — | EP | disclosed |
| EP-0023633-A1 | Pyrazoloindazole derivatives and process for preparing the same and pharmaceutical compositions | Chugai Seiyaku Kabushiki Kaisha (JP) | 1981-02-11 | — | — | EP | disclosed |