Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | PLAT | P00750 | 2/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | KLK8 | O60259 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255533 | 0.90 | ATM (0.77) | ATMCTSLCTSSCTRB1MEN1 | |
| SCHEMBL7719287 | 0.90 | ATM (0.77) | ATMCTSLCTSSCTRB1MEN1 | |
| SCHEMBL1362502 | 0.90 | ATM (0.77) | ATMCTSLCTSSCTRB1MEN1 | |
| SCHEMBL434233 | 0.90 | ATM (0.77) | ATMCTSLCTSSCTRB1MEN1 | |
| SCHEMBL5742261 | 0.89 | ATM (0.67) | ATMCTSLCTSSCTRB1LMNA | |
| SCHEMBL5742255 | 0.89 | ATM (0.67) | ATMCTSLCTSSCTRB1LMNA | |
| SCHEMBL17765000 | 0.89 | ATM (0.67) | ATMCTSLCTSSCTRB1LMNA | |
| SCHEMBL28224944 | 0.86 | ATM (0.64) | ATMCTSLCTSSCTRB1CNR2 | |
| SCHEMBL28224943 | 0.86 | ATM (0.64) | ATMCTSLCTSSCTRB1CNR2 | |
| SCHEMBL6736883 | 0.85 | ATM (0.70) | ATMCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090240-A2 | 7-Alpha-aminoacyl-3-chlorocephalosporins, their preparation and their use as pharmaceutical products | BAYER AG (DE) | 1983-10-05 | — | — | EP | disclosed |