Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.63 |
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP3 | P08254 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069255 | 0.91 | MME (0.71) | MMEACEMMP2LTA4HMMP7 | |
| SCHEMBL10947100 | 0.87 | MME (0.65) | MMEACELTA4HCPA1ACE2 | |
| SCHEMBL11205478 | 0.87 | BIRC2 (0.59) | — | |
| SCHEMBL8249153 | 0.87 | MME (0.62) | MMEACEMMP3LTA4HMMP9 | |
| SCHEMBL5869766 | 0.87 | MME (0.62) | MMEACEMMP3LTA4HMMP9 | |
| SCHEMBL8248719 | 0.87 | MME (0.62) | MMEACEMMP3LTA4HMMP9 | |
| SCHEMBL8248581 | 0.87 | MME (0.62) | MMEACEMMP3LTA4HMMP9 | |
| SCHEMBL8248814 | 0.87 | MME (0.62) | MMEACEMMP3LTA4HMMP9 | |
| SCHEMBL7374357 | 0.85 | MME (0.67) | MMEACEMMP2MMP7MMP9 | |
| SCHEMBL17948648 | 0.85 | CPA1 (0.63) | MMEACEMMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079521-A1 | Process for preparation of carboxyalkyldipeptide derivatives | MERCK & CO. INC. (US) | 1983-05-25 | — | — | EP | claimed |
| EP-0079521-A1 | Process for preparation of carboxyalkyldipeptide derivatives | MERCK & CO. INC. (US) | 1983-05-25 | — | — | EP | disclosed |