Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206173 | 1.00 | TDP1 (0.46) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL3844497 | 0.93 | TDP1 (0.53) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL27463563 | 0.93 | TDP1 (0.53) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL27463562 | 0.93 | TDP1 (0.53) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL27463564 | 0.93 | TDP1 (0.53) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL3844494 | 0.93 | TDP1 (0.53) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL9247166 | 0.83 | TDP1 (0.63) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL11039301 | 0.83 | TDP1 (0.63) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL9247169 | 0.83 | TDP1 (0.63) | TDP1ALDH1A1ALOX5KMT2AMAPT | |
| SCHEMBL5604454 | 0.83 | TDP1 (0.63) | TDP1ALDH1A1ALOX5KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091208-A1 | Method for combating insect pests, and novel cyclopropane carboxylates useful as active ingredients therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-10-12 | — | — | EP | claimed |