SCHEMBL11206207

SCHEMBL11206207

OCC/C(=C(/c1ccccc1)c1ccc(O)cc1)c1ccc(O)cc1.Oc1ccc(/C(CCBr)=C(\c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.61
ESRRG P62508 11/20 0.56
CYP19A1 P11511 3/20 0.56
ESR2 Q92731 2/20 0.56
ESRRB O95718 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11206212 1.00 ESR1 (0.61) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL1152608 0.93 ESR1 (0.69) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL1152610 0.93 ESR1 (0.69) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL1151879 0.92 ESR1 (0.71) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL2229348 0.92 ESR1 (0.71) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL1151986 0.92 ESR1 (0.71) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL1151880 0.92 ESR1 (0.71) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL5725055 0.92 ESR1 (0.71) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL1151987 0.92 ESR1 (0.71) ESR1ESRRGCYP19A1ESR2ESRRB
SCHEMBL5726578 0.84 ESR1 (0.61) ESR1ESRRGCYP19A1ESR2ESRRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095875-A2 Novel tri-phenyl alkane and alkene derivatives and their preparation and use Farmos Group Ltd. (FI) 1983-12-07 EP disclosed