Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729438 | 0.90 | HTT (0.68) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL755913 | 0.90 | HTT (0.68) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11216634 | 0.89 | HTT (0.66) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11220203 | 0.87 | HTT (0.64) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11207238 | 0.87 | TDP1 (0.67) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11220987 | 0.87 | HTT (0.64) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL30729436 | 0.87 | HTT (0.59) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2084753 | 0.86 | HTT (0.67) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2471335 | 0.84 | HTT (0.60) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9518917 | 0.84 | HTT (0.60) | HTTTDP1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014432-B1 | WATER SOLUBLE FIBRE REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING FIBROUS MATERIALS CONTAINING HYDROXYL AND CARBONAMIDE GROUPS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0011843-B1 | DEVELOPING COMPONENTS FOR HAIR OXYDATION DYES, THEIR PREPARATION AND HAIR DYES CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-09-15 | — | — | EP | disclosed |
| US-4231964-A | Nitroamines, processes for their manufacture and their use as diazo components | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-04 | — | — | US | disclosed |
| EP-0014432-A2 | Water soluble fibre reactive disazo dyes, process for their preparation and their use for dyeing and printing fibrous materials containing hydroxyl and carbonamide groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-20 | — | — | EP | disclosed |
| EP-0011843-A2 | Developing components for hair oxydation dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |