Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 10/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.46 |
| ▸ | NPY1R | P25929 | 5/20 | 0.46 |
| ▸ | NPY2R | P49146 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | GLP1R | P43220 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352509 | 0.99 | NPY4R (0.47) | NPY4RNPY5RNPY1RNPY2RFNTA | |
| SCHEMBL9069166 | 0.95 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2RFNTA | |
| SCHEMBL11347759 | 0.90 | NPY4R (0.46) | NPY4RNPY5RNPY1RNPY2RFNTA | |
| SCHEMBL9068526 | 0.90 | NPY4R (0.40) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL10919416 | 0.89 | NPY4R (0.39) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL11205897 | 0.86 | FNTA (0.52) | NPY4RNPY5RNPY1RNPY2RFNTA | |
| SCHEMBL10918462 | 0.85 | NPY4R (0.44) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL9068939 | 0.85 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL11210708 | 0.85 | FNTA (0.53) | NPY4RNPY5RNPY1RNPY2RFNTA | |
| SCHEMBL11210310 | 0.85 | FNTA (0.53) | NPY4RNPY5RNPY1RNPY2RFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021766-B1 | INHIBITORS OF MAMMALIAN COLLAGENASE | E.R. Squibb & Sons, Inc. (US) | 1983-02-09 | — | — | EP | disclosed |
| US-4297275-A | Inhibitors of mammalian collagenase | E. R. SQUIBB & SONS, INC. (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0021766-A2 | Inhibitors of mammalian collagenase | E.R. Squibb & Sons, Inc. (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4235885-A | Inhibitors of mammalian collagenase | E. R. SQUIBB & SONS, INC. (US) | 1980-11-25 | — | — | US | disclosed |