Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 11/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120829 | 0.91 | ADRB3 (0.49) | ADRB3ADRA1AADRB2ADRB1 | |
| SCHEMBL1120894 | 0.89 | ADRB3 (0.66) | ADRB3ADRA1AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL1120918 | 0.88 | ADRB3 (0.65) | ADRB3ADRA1AADRB2ADRB1 | |
| SCHEMBL1120787 | 0.87 | ADRB3 (0.50) | ADRB3ADRA1A | |
| SCHEMBL1120897 | 0.84 | ADRB3 (0.49) | ADRB3ADRA1A | |
| Benzene SCHEMBL27617450 | 0.84 | MAPT (0.40) | MMP2MMP13 | |
| SCHEMBL1120879 | 0.82 | ADRB3 (0.62) | ADRB3ADRA1A | |
| SCHEMBL1120795 | 0.80 | ADRB3 (0.67) | ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL1120841 | 0.79 | ADRB3 (0.66) | ADRB3ADRA1A | |
| SCHEMBL1120882 | 0.79 | ADRB3 (0.68) | ADRB3ADRA1AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935882-B1 | Bicyclic compounds | ASAHI KASEI PHARMA CORP (JP) | 2011-02-09 | — | — | EP | claimed |
| EP-1935882-B1 | Bicyclic compounds | ASAHI KASEI PHARMA CORP (JP) | 2011-02-09 | — | — | EP | disclosed |
| US-7511069-B2 | Indazole compounds as β3 andrenoceptor agonist | ASAHI PHARMA CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |