Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282045 | 0.89 | TSHR (0.50) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL29127700 | 0.85 | TSHR (0.47) | TSHRGABRA1GABRB2ALDH1A1MAPT | |
| SCHEMBL5589049 | 0.85 | BCHE (0.43) | TSHRGABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL11103603 | 0.83 | TSHR (0.63) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL1268939 | 0.80 | TSHR (0.44) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL983828 | 0.79 | TSHR (0.57) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL3001397 | 0.79 | TSHR (0.57) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL352351 | 0.78 | TSHR (0.73) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL4738271 | 0.78 | TSHR (0.55) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL6679941 | 0.78 | NISCH (0.43) | TSHRLMNAKDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115144137-A | Substitution method for full water test of large water treatment and storage structure | 中建三局绿色产业投资有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-212758571-U | A reation kettle agitating unit for producing chloroprene phenol aldehyde adhesive | 常熟市江南粘合剂有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-212758571-U | A reation kettle agitating unit for producing chloroprene phenol aldehyde adhesive | 常熟市江南粘合剂有限公司 | 2021-03-23 | — | — | CN | disclosed |
| EP-0005053-B1 | FLAME-RETARDANT ORGANIC PHOSPHATES, THEIR PRODUCTION, AND COMPOSITIONS CONTAINING THEM | FMC Corporation (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4246169-A | Flammable plastics containing a flame retardant amount of polyarylphosphates and the polyarylphosphates | FMC CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| EP-0005053-A2 | Flame-retardant organic phosphates, their production, and compositions containing them | FMC Corporation (US) | 1979-10-31 | — | — | EP | disclosed |