Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14508861 | 0.90 | HDAC8 (0.59) | AKR1C3HDAC8HDAC3CA12CA1 | |
| SCHEMBL5485331 | 0.85 | TDP1 (0.69) | AKR1C3HDAC1HDAC7HDAC6GAA | |
| SCHEMBL13485791 | 0.85 | NR4A1 (0.66) | AKR1C3GAAKDM4EMPOSMN1; SMN2 | |
| SCHEMBL13485824 | 0.85 | GAA (0.50) | AKR1C3HDAC8HDAC3CA12CA1 | |
| SCHEMBL1331243 | 0.84 | GAA (0.73) | HDAC8HDAC3CA12CA1IDO1 | |
| SCHEMBL29447165 | 0.84 | AKR1C3 (0.85) | AKR1C3HSD17B10GAAKDM4EMAPT | |
| SCHEMBL700595 | 0.84 | AKR1C3 (0.85) | AKR1C3HSD17B10GAAKDM4EMAPT | |
| SCHEMBL11504870 | 0.83 | AKR1C3 (0.63) | AKR1C3GAAMAPTTDP1ALDH1A1 | |
| SCHEMBL28883310 | 0.82 | AKR1C3 (0.81) | AKR1C3HSD17B10GAAKDM4ESMN1; SMN2 | |
| Fluoride SCHEMBL28319246 | 0.82 | AKR1C3 (0.81) | AKR1C3HSD17B10GAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035291-B1 | PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT | AKZO N.V. (NL) | 1983-05-11 | — | — | EP | disclosed |