SCHEMBL11208606

SCHEMBL11208606

CC1(C)CC1C=C(Cl)C(F)(F)F.O=C(O)Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11210489 1.00 MEN1 (0.35) MEN1KMT2ATDP1
SCHEMBL5197845 1.00 MEN1 (0.35) MEN1KMT2ATDP1
Bicarbonate SCHEMBL5196976 0.96 MEN1 (0.35) MEN1KMT2ATDP1
Bicarbonate SCHEMBL5686126 0.96 MEN1 (0.35) MEN1KMT2ATDP1
Bicarbonate SCHEMBL7600398 0.96 MEN1 (0.35) MEN1KMT2ATDP1
SCHEMBL4623998 0.96 MEN1 (0.36) MEN1KMT2ATDP1
SCHEMBL5399203 0.96 MEN1 (0.36) MEN1KMT2ATDP1
SCHEMBL25261479 0.92 MEN1 (0.32) MEN1KMT2ATDP1
SCHEMBL3365310 0.92 MEN1 (0.32) MEN1KMT2ATDP1
SCHEMBL3365312 0.92 MEN1 (0.32) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012150206-A2 NOVEL CYCLOPROPANOIC ACID ESTER DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
WO-2012150205-A1 NOVEL SUBSTITUTED BENZYL ALCOHOL ESTERS OF CYCLOPROPANECARBOXYLIC ACID AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
WO-2012150223-A1 NOVEL PYRIDINE METHYL ESTERS OF CYCLOPROPANE CARBOXYLIC ACID AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
WO-2012150207-A1 USE OF CYCLOPROPANECARBOXYLIC ACID ESTER DERIVATIVES FOR CONTROLLING INSECTICIDE-RESISTANT INSECTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
WO-2012150221-A2 NOVEL HALOGENATED BENZYL ALCOHOL ESTERS OF CYCLOPROPANE CARBOXYLIC ACID AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
WO-2012150208-A1 USE OF SUBSTITUTED BENZYL ALCOHOL ESTERS OF CYCLOPROPANECARBOXYLIC ACID FOR CONTROLLING INSECTICIDE-RESISTANT INSECTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
EP-0008340-B1 FLUOROALKENYL-SUBSTITUTED CYCLOPROPANECARBOXYLIC ACID ESTERS, INTERMEDIATE PRODUCTS THEREFOR, PREPARATION OF THE COMPOUNDS AND THEIR UTILIZATION AS INSECTICIDES AND/OR ACARICIDES BAYER AG (DE) 1983-12-21 EP disclosed