SCHEMBL11208683

SCHEMBL11208683

Oc1ccc(-c2cccc(-c3ccccc3)c2-c2ccc(O)cc2)cc1.SS

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 2/20 0.58
MMP3 P08254 2/20 0.58
ABL1 P00519 1/20 0.52
ABCB1 P08183 1/20 0.52
BCR P11274 1/20 0.52
ALOX5 P09917 1/20 0.48
ESR1 P03372 3/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PDE4A P27815 2/20 0.47
PDE4B Q07343 2/20 0.47
PDE4C Q08493 2/20 0.47
PDE4D Q08499 2/20 0.47
ESR2 Q92731 3/20 0.47
HNF4A P41235 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28208904 0.98 BCL2L1 (0.61) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL4651419 0.98 BCL2L1 (0.61) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL2399392 0.98 BCL2L1 (0.61) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL2399395 0.98 BCL2L1 (0.61) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL28090399 0.96 BCL2L1 (0.58) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL951244 0.91 ABL1 (0.54) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL6448576 0.91 ABL1 (0.54) BCL2L1MMP3ABL1ABCB1BCR
Hydrochloric Acid SCHEMBL28960654 0.89 ABL1 (0.52) BCL2L1MMP3ABL1ABCB1BCR
SCHEMBL28046566 0.89 ESR1 (0.55) BCL2L1MMP3ABL1ABCB1BCR
Benzidine SCHEMBL5572493 0.87 HSD17B10 (0.54) BCL2L1MMP3ABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0082384-A1 A process for the preparation of bis(4-hydroxyphenyl)biphenyl disulfone MOBAY CORPORATION (US) 1983-06-29 EP disclosed