Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603313 | 0.85 | TSHR (0.53) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL23754669 | 0.78 | TSHR (0.71) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL320487 | 0.78 | — | — | |
| SCHEMBL1014174 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL5324654 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL4197788 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL449061 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL5322089 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL180355 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 | |
| SCHEMBL5492137 | 0.76 | TSHR (0.67) | TSHRCA1CA9ALDH1A1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365086-A | CURING AGENTS FOR THERMOPLASTIC ELASTOMERS | PENNWALT CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4328360-A | VULCANIZING AGENT FOR THERMOPLASTIC RESINS | PENNWALT CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |