Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 12/20 | 0.60 |
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | CTSB | P07858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CTSG | P08311 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213032 | 0.99 | CAPN1 (0.59) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10858698 | 0.90 | CAPN1 (0.57) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10858704 | 0.90 | CAPN1 (0.57) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10858709 | 0.90 | CAPN1 (0.57) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL20628822 | 0.83 | CAPN1 (0.47) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10861352 | 0.83 | CAPN1 (0.54) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10861340 | 0.83 | CAPN1 (0.54) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10861379 | 0.83 | CAPN1 (0.54) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10855985 | 0.82 | CAPN1 (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL10855992 | 0.82 | CAPN1 (0.60) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382889-A | Epoxysuccinic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| US-4333879-A | CALCIUM-ACTIVATED NEUTRAL THIOLPROTEASE INHIBITOR USED IN THE TREATMENT OF MUSCULAR DYSTROPHY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |