Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413540 | 0.82 | PTPN1 (0.54) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL2902587 | 0.79 | — | — | |
| SCHEMBL2808310 | 0.79 | PTPN1 (0.60) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL2804264 | 0.79 | PTPN1 (0.55) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL19495977 | 0.79 | — | — | |
| SCHEMBL3253304 | 0.79 | PHF8 (0.55) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL10056657 | 0.77 | PTPN1 (0.63) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL30838582 | 0.77 | PTPN1 (0.63) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL8505361 | 0.77 | PTPN1 (0.63) | FAAHALDH1A1PTPN1MEN1KMT2A | |
| SCHEMBL31336114 | 0.77 | PTPN1 (0.63) | FAAHALDH1A1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086757-A1 | Derivatives of alpha or beta-mercaptopropionylamidoacetic acids, processes for their preparation and the therapeutic compositions which include them as active principles | Farmatis S.r.l. (IT) | 1983-08-24 | — | — | EP | disclosed |
| EP-0015544-B1 | DERIVATIVES OF THE MERCAPTOPROPIONAMIDO-ACETIC ACID, PROCESS FOR THE PREPARATION THEREOF AND COMPOSITIONS | ZAMBON S.p.A. (IT) | 1983-01-05 | — | — | EP | disclosed |
| EP-0015544-A2 | Derivatives of the mercaptopropionamido-acetic acid, process for the preparation thereof and compositions | ZAMBON S.p.A. (IT) | 1980-09-17 | — | — | EP | disclosed |