Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143532 | 0.88 | HRH2 (0.74) | HRH2HRH3ALDH1A1KDM4E | |
| SCHEMBL11391628 | 0.88 | HRH2 (0.61) | HRH2HRH3ALDH1A1KDM4E | |
| SCHEMBL11177820 | 0.87 | HRH2 (0.59) | HRH2HRH3ALDH1A1KDM4E | |
| SCHEMBL11179207 | 0.87 | HRH2 (0.78) | HRH2HRH3 | |
| SCHEMBL11191281 | 0.84 | HRH2 (0.60) | HRH2HRH3 | |
| SCHEMBL11184068 | 0.84 | HRH2 (0.63) | HRH2HRH3 | |
| SCHEMBL11378960 | 0.82 | HRH2 (0.54) | HRH2HRH3 | |
| SCHEMBL11387345 | 0.82 | HRH2 (0.54) | HRH2HRH3 | |
| SCHEMBL5291389 | 0.81 | HRH2 (0.58) | HRH2HRH3ALDH1A1KDM4E | |
| SCHEMBL5277819 | 0.81 | HRH2 (0.69) | HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024510-B1 | PHENOXYPROPYL AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1983-10-19 | — | — | EP | disclosed |