Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.77 |
| ▸ | TSHR | P16473 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CBR1 | P16152 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177878 | 0.88 | — | — | |
| SCHEMBL19553825 | 0.88 | HSD17B10 (1.00) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Potassium SCHEMBL31408934 | 0.85 | HSD17B10 (0.94) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Potassium SCHEMBL31408932 | 0.85 | HSD17B10 (0.94) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL16824107 | 0.85 | HSD17B10 (0.94) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Potassium SCHEMBL31408933 | 0.85 | HSD17B10 (0.94) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Hydrogen Sulfide SCHEMBL11712057 | 0.81 | HSD17B10 (0.68) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL11712063 | 0.81 | HSD17B10 (0.68) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| 1,2-Dichlorobenzene SCHEMBL3658265 | 0.79 | HSD17B10 (0.81) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| 2,4-Dichlorophenol SCHEMBL11402173 | 0.79 | HSD17B10 (0.81) | HSD17B10TSHRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037985-B1 | PHOTOGRAPHIC MATERIAL AND COMPOUNDS FOR USE THEREIN, AND THAT RELEASE A PHOTOGRAPHICALLY ACTIVE MOIETY | Agfa-Gevaert AG (DE) | 1983-06-15 | — | — | EP | disclosed |
| EP-0037985-A1 | Photographic material and compounds for use therein, and that release a photographically active moiety | Agfa-Gevaert AG (DE) | 1981-10-21 | — | — | EP | disclosed |