Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TTR | P02766 | 6/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944937 | 0.97 | NPC1 (0.52) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL10944576 | 0.93 | NPC1 (0.60) | NPC1RAB9ATTRKDM4EALDH1A1 | |
| SCHEMBL10948255 | 0.90 | NPC1 (0.64) | NPC1RAB9ATTRKDM4EALDH1A1 | |
| SCHEMBL10948185 | 0.83 | NPC1 (0.53) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL10941262 | 0.80 | NPC1 (0.56) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL10945260 | 0.79 | KDM4E (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10943083 | 0.78 | KDM4E (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10945176 | 0.77 | NPC1 (0.65) | NPC1RAB9ATTRKDM4EALDH1A1 | |
| SCHEMBL10942675 | 0.76 | KDM4E (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10948079 | 0.76 | NPC1 (0.49) | NPC1RAB9ATTRAKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |