SCHEMBL11210067

SCHEMBL11210067

Cc1cccc(C)c1CCCl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 2/20 0.41
TSHR P16473 1/20 0.40
ACHE P22303 1/20 0.40
ALDH1A1 P00352 5/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
TAAR1 Q96RJ0 4/20 0.36
HTR1D P28221 1/20 0.35
TRPA1 O75762 2/20 0.35
CD44 P16070 1/20 0.35
ATM Q13315 1/20 0.35
MAPT P10636 2/20 0.34
AHR P35869 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11858483 0.85 TAAR1 (0.40) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8093986 0.85 CYP2A6 (0.47) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8095408 0.82 CYP2A6 (0.45) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8096178 0.82 CYP2A6 (0.45) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL16974983 0.80 TAAR1 (0.36) CYP2A6CYP1A2ALDH1A1CA1CA2
SCHEMBL8097070 0.80 CYP2A6 (0.43) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8101082 0.80 CYP2A6 (0.43) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8087584 0.80 CYP2A6 (0.43) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8093240 0.80 CYP2A6 (0.43) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL8096579 0.80 CYP2A6 (0.43) CYP2A6CYP1A2TSHRACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed
EP-0072615-A1 Substituted imidazole derivatives and their preparation and use Farmos Group Ltd. (FI) 1983-02-23 EP disclosed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US disclosed