Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205811 | 0.86 | TAAR1 (0.32) | TAAR1 | |
| SCHEMBL11210132 | 0.84 | TAAR1 (0.39) | TAAR1DHFR | |
| SCHEMBL11235805 | 0.83 | TAAR1 (0.36) | TAAR1P2RX7ADRA2AADRA2BADRA2C | |
| SCHEMBL10795323 | 0.82 | MEN1 (0.33) | TAAR1 | |
| SCHEMBL10789648 | 0.80 | TAAR1 (0.38) | TAAR1DAOP2RX7 | |
| SCHEMBL11206110 | 0.79 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL10793183 | 0.78 | TAAR1 (0.39) | TAAR1CYP19A1DAOGPR84P2RX7 | |
| SCHEMBL10789680 | 0.77 | TAAR1 (0.38) | TAAR1DAODHFR | |
| SCHEMBL11207952 | 0.77 | TAAR1 (0.34) | TAAR1 | |
| SCHEMBL11204976 | 0.75 | TAAR1 (0.41) | TAAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |
| EP-0034474-A1 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |