Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096529 | 0.86 | HIF1A (0.41) | KMT2AHIF1AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11204799 | 0.85 | CPA1 (0.43) | MEN1KMT2AHIF1AALDH1A1MAPT | |
| SCHEMBL11208204 | 0.80 | SCN1A (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11210561 | 0.78 | HIF1A (0.45) | HIF1AMAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL11208465 | 0.77 | HIF1A (0.44) | HIF1AMAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL4983840 | 0.75 | HIF1A (0.42) | HIF1AALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL11211934 | 0.74 | HIF1A (0.43) | ESR1ESR2HIF1AALDH1A1MAPT | |
| SCHEMBL1234209 | 0.73 | ESR1 (0.68) | ATMESR1ESR2MEN1KMT2A | |
| SCHEMBL25215975 | 0.69 | PSMB5 (0.48) | ATMESR1ESR2MEN1KMT2A | |
| SCHEMBL684343 | 0.69 | ATM (0.48) | ATMESR1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |