SCHEMBL11211298

SCHEMBL11211298

CCNC(=O)C1(CCCN)c2ccccc2-c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTTP P55157 1/20 0.46
PDK2 Q15119 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6675984 0.96 MTTP (0.47) MTTP
SCHEMBL6648015 0.85 MTTP (0.46) MTTPPDK2
SCHEMBL5863393 0.84 MTTP (0.47) MTTPPDK2
SCHEMBL11478909 0.83 MTTP (0.44) MTTP
Isopropylamine SCHEMBL11190763 0.83 MTTP (0.49) MTTP
SCHEMBL11084972 0.82 PDK2 (0.39) MTTPPDK2
SCHEMBL20066245 0.81 MTTP (0.67) MTTP
SCHEMBL10778218 0.79 APEX1 (0.42) PDK2
SCHEMBL11190769 0.77 MTTP (0.40) MTTP
SCHEMBL11190756 0.77 MTTP (0.42) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018076-B1 9-AMINOALKYLFLUORENES, PROCESS THEREFOR AND ANTIARRHYTHMIC FORMULATIONS THEREOF ELI LILLY AND COMPANY (US) 1983-09-21 EP disclosed
EP-0018076-A1 9-Aminoalkylfluorenes, process therefor and antiarrhythmic formulations thereof ELI LILLY AND COMPANY (US) 1980-10-29 EP disclosed