⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498825 | 0.73 | — | — | |
| SCHEMBL10721015 | 0.73 | — | — | |
| SCHEMBL9357778 | 0.71 | — | — | |
| SCHEMBL171442 | 0.69 | — | — | |
| SCHEMBL15264608 | 0.69 | — | — | |
| SCHEMBL676154 | 0.69 | — | — | |
| SCHEMBL10771284 | 0.67 | — | — | |
| SCHEMBL2160295 | 0.67 | — | — | |
| SCHEMBL5014195 | 0.65 | — | — | |
| SCHEMBL336532 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390711-A | 16-Hydroxy-5-iodo-prostacyclin analogs of the 1 series | AMERICAN CYANAMID COMPANY (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0052204-A1 | Prostacyclin analogs of the 1 series and related analogs | AMERICAN CYANAMID COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
| US-4265904-A | BRONCHODILATOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4235924-A | BRONCHODILATION, PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |