SCHEMBL112119

SCHEMBL112119

NCc1ccc(Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL28970937 0.97 TAAR1 (0.59)
Bromide SCHEMBL29023877 0.97 TAAR1 (0.59)
Methane SCHEMBL10520385 0.97 TAAR1 (0.59)
Hydrochloric Acid SCHEMBL161528 0.97 TAAR1 (0.59)
Hydrochloric Acid SCHEMBL28560181 0.94 TAAR1 (0.56)
SCHEMBL5828443 0.92 HRH3 (0.74)
SCHEMBL28384280 0.89 TAAR1 (0.52)
SCHEMBL17967545 0.87 MAOB (0.53)
SCHEMBL6158673 0.85 ST14 (0.68)
Hydrochloric Acid SCHEMBL921495 0.83 ST14 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2399 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
CN-119977906-A A-site cation-regulated halide perovskite, and preparation method and application thereof 西北大学 2025-05-13 CN claimed
CN-119708528-A Cd-MOF material and preparation method and application thereof 山西师范大学 2025-03-28 CN claimed
CN-118976370-B Positively charged nanofiltration membrane based on quaternized monomers and preparation method and application thereof 同济大学 2025-03-21 CN claimed
CN-119528816-A PARP-1 inhibitor and preparation method thereof 吉林省药物研究院 2025-02-28 CN claimed
CN-119019410-B Adenosine triphosphate aggregation-induced emission compound, and preparation method and application thereof 广东工业大学 2025-02-14 CN claimed
CN-119140080-B Titanium oxide film catalytic material for rapid high-yield synthesis of imine and preparation method and application thereof 中国科学院理化技术研究所 2025-02-11 CN claimed
CN-119140080-A Titanium oxide film catalytic material for rapid high-yield synthesis of imine and preparation method and application thereof 中国科学院理化技术研究所 2024-12-17 CN claimed
CN-119118901-A Oxindole derivative, preparation method thereof and application thereof in TRPA1 inhibitor direction 中国人民解放军北部战区总医院 2024-12-13 CN claimed
CN-118702715-B Nitrosoperoxide aggregation-induced emission compound, and preparation method and application thereof 广东工业大学 2024-11-29 CN claimed
WO-2001068605-A1 POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-09-20 WO claimed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 EP claimed
WO-2001019779-A1 PREPARATION OF HALOGENATED PRIMARY AMINES ALLIEDSIGNAL INC. (US) 2001-03-22 WO claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed
EP-0863877-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INST (US) 1999-07-21 EP claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
CN-1202888-A Isoquinoline derivatives and isoquinoline combinatorial libraries TORREY PINES INST (US) 1998-12-23 CN claimed
EP-0863877-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-09-16 EP claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed