Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212105 | 0.92 | ACE (0.42) | ACE | |
| SCHEMBL11215539 | 0.84 | ACE (0.32) | ACE | |
| SCHEMBL11212457 | 0.82 | ACE (0.34) | ACE | |
| SCHEMBL11214081 | 0.79 | ACE (0.41) | ACE | |
| SCHEMBL11257080 | 0.78 | ACE (0.37) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11210160 | 0.78 | ACE (0.37) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11212958 | 0.77 | ACE (0.38) | ACE | |
| SCHEMBL11210147 | 0.76 | ACE (0.50) | ACE | |
| SCHEMBL11214777 | 0.76 | ACE (0.50) | ACE | |
| SCHEMBL11212494 | 0.76 | ACE (0.31) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |