Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314665 | 0.87 | NPC1 (0.57) | NPC1RAB9AKDM4ENPSR1RXFP1 | |
| SCHEMBL683708 | 0.86 | KDM4E (0.70) | NPC1RAB9AKDM4ENPSR1RXFP1 | |
| SCHEMBL11787853 | 0.84 | MEN1 (0.53) | NPC1RAB9AKDM4ENPSR1MEN1 | |
| SCHEMBL11309849 | 0.84 | GAA (0.56) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11313281 | 0.83 | NPC1 (0.60) | NPC1RAB9AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL27742408 | 0.82 | JAK2 (0.49) | NPC1RAB9AKDM4ENPSR1RXFP1 | |
| SCHEMBL11787139 | 0.82 | MAPT (0.51) | NPC1RAB9AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL11174674 | 0.78 | JAK2 (0.57) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11789934 | 0.78 | HDAC1 (0.59) | NPC1RAB9AKDM4ENPSR1RXFP1 | |
| SCHEMBL10893718 | 0.78 | HDAC1 (0.72) | NPC1RAB9AKDM4ENPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941768-A | One step diazotization coupling process | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | claimed |
| US-4314938-A | Iminoisoindolinone pigments containing phenylazoacetoacetyl-aminophenylene groups | CIBA-GEIGY CORPORATION (US) | 1982-02-09 | — | — | US | disclosed |
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4031073-A | Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |
| US-3941768-A | One step diazotization coupling process | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |