Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | PPOX | P50336 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238106 | 0.88 | TDP1 (0.58) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11854430 | 0.88 | TDP1 (0.58) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL29448825 | 0.88 | TDP1 (0.58) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11212778 | 0.87 | TDP1 (0.57) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL8376803 | 0.86 | TDP1 (0.56) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10661113 | 0.86 | TDP1 (0.56) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10662019 | 0.86 | TDP1 (0.56) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11125892 | 0.86 | TDP1 (0.56) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL8382106 | 0.85 | TDP1 (0.55) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11848309 | 0.85 | TDP1 (0.55) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075377-A2 | Diphenyl ether compounds, their use as herbicides, and herbicidal compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-03-30 | — | — | EP | disclosed |