Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL11212650

CC=Cc1ccccc1.OCCOCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
RECQL P46063 1/20 0.41
AKR1B10 O60218 1/20 0.40
AKR1B1 P15121 1/20 0.40
TSHR P16473 2/20 0.39
CHAT P28329 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
KDM4E B2RXH2 1/20 0.39
RELA Q04206 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.39
TRPA1 O75762 1/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAOB P27338 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL598949 0.86 MAOB (0.46) ALDH1A1RECQLTSHRCHATLMNA
Tetraethylene Glycol SCHEMBL1618779 0.79 MEN1 (0.41) ALDH1A1RECQLAKR1B10AKR1B1TSHR
Methyl Alcohol SCHEMBL10861893 0.79 MAOB (0.52) ALDH1A1RECQLTSHRCHATLMNA
Benzene SCHEMBL1225177 0.78 MAOB (0.58) ALDH1A1RECQLTSHRCHATLMNA
SCHEMBL335864 0.78
SCHEMBL2342 0.78
SCHEMBL28967 0.78
Benzene SCHEMBL1225180 0.78 MAOB (0.58) ALDH1A1RECQLTSHRCHATLMNA
SCHEMBL671163 0.78 MAOB (0.58) ALDH1A1RECQLTSHRCHATLMNA
SCHEMBL25430836 0.78 MEN1 (0.40) ALDH1A1RECQLAKR1B10AKR1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044832-A4 PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES. BLOUNT DAVID H 1982-07-06 EP disclosed
EP-0044832-A1 PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES BLOUNT, David H. (US) 1982-02-03 EP disclosed
WO-1981002300-A1 PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES BLOUNT D 1981-08-20 WO disclosed