Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 10/20 | 0.35 |
| ▸ | GBA1 | P04062 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211887 | 1.00 | CES1 (0.49) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL11209987 | 0.94 | CES1 (0.53) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL10993366 | 0.94 | CES1 (0.53) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL28385756 | 0.94 | CES1 (0.53) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL7035407 | 0.94 | CES1 (0.53) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL10986732 | 0.92 | CES1 (0.50) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL2349435 | 0.90 | CES1 (0.48) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL9023823 | 0.86 | TSHR (0.50) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL27829650 | 0.83 | CES1 (0.50) | CES1HTTMEN1THRBKMT2A | |
| SCHEMBL28138332 | 0.83 | CES1 (0.50) | CES1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019349-B1 | STABILIZING COMPOSITION FOR POLYARYLENE ESTERS, STABILIZED POLYARYLENE ESTER, MOULDED ARTICLE PRODUCED THEREFROM AND PROCESS FOR STABILIZING A POLYARYLENE ESTER | MONSANTO COMPANY (US) | 1983-08-03 | — | — | EP | disclosed |
| EP-0019349-A1 | Stabilizing composition for polyarylene esters, stabilized polyarylene ester, moulded article produced therefrom and process for stabilizing a polyarylene ester | MONSANTO COMPANY (US) | 1980-11-26 | — | — | EP | disclosed |
| US-4222932-A | MOLDING MATERIALS STABILIZED BY ADDING AN AROMATIC ISOCYANATE AND AN ALIPHATIC PHOSPHITE | MONSANTO COMPANY (US) | 1980-09-16 | — | — | US | disclosed |