Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323450 | 0.86 | RECQL (0.44) | RECQLTSHRKMT2ALMNAMAPT | |
| SCHEMBL12637270 | 0.80 | GAA (0.38) | RECQLTSHRKMT2ALMNAMAPT | |
| SCHEMBL16678900 | 0.80 | RECQL (0.38) | RECQLTSHRKMT2AL3MBTL1MEN1 | |
| SCHEMBL17947394 | 0.79 | RECQL (0.39) | RECQLTSHRKMT2ALMNAMAPT | |
| SCHEMBL11085648 | 0.79 | RECQL (0.39) | RECQLTSHRKMT2ALMNAMAPT | |
| SCHEMBL10743325 | 0.77 | GAA (0.43) | RECQLTSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8430842 | 0.77 | TSHR (0.43) | RECQLTSHRKMT2AL3MBTL1MEN1 | |
| SCHEMBL2901200 | 0.76 | RECQL (0.52) | RECQLTSHRKMT2ALMNAMAPT | |
| SCHEMBL11139939 | 0.76 | GAA (0.41) | RECQLTSHRKMT2ALMNAMAPT | |
| SCHEMBL10444750 | 0.76 | POLB (0.45) | RECQLTSHRKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322531-A | Diazaphospholanes and diazaphosphorinanes | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |