⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355288 | 0.59 | — | — | |
| SCHEMBL7506785 | 0.57 | — | — | |
| SCHEMBL8524652 | 0.57 | — | — | |
| SCHEMBL324918 | 0.56 | — | — | |
| SCHEMBL3754347 | 0.56 | — | — | |
| SCHEMBL921850 | 0.54 | — | — | |
| SCHEMBL2729732 | 0.52 | — | — | |
| SCHEMBL4706422 | 0.51 | MEN1 (0.30) | — | |
| SCHEMBL8654978 | 0.50 | TDP1 (0.53) | — | |
| SCHEMBL7149902 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003732-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-10-19 | — | — | EP | disclosed |