Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162243 | 0.81 | ESR1 (0.48) | ESR1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL6715858 | 0.81 | ESR1 (0.44) | ESR1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL7758677 | 0.78 | CA1 (0.56) | ESR1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL28334190 | 0.74 | ESR1 (0.49) | ESR1LMNAPPARGPTGESALOX5 | |
| SCHEMBL9303185 | 0.74 | ESR1 (0.55) | ESR1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL27794811 | 0.74 | ESR1 (0.55) | ESR1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL10809828 | 0.74 | ESR1 (0.50) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL5326614 | 0.74 | ESR1 (0.50) | ESR1LMNAPPARGPTGESALOX5 | |
| SCHEMBL14247171 | 0.74 | ESR1 (0.46) | ESR1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL9846651 | 0.73 | ESR1 (0.47) | ESR1LMNAPPARGPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010346-B1 | POLYOLEFINS STABILIZED AGAINST LIGHT-INDUCED DEGRADATION AND A LIGHT STABILIZER COMPOSITION THEREFOR | AMERICAN CYANAMID COMPANY (US) | 1983-10-12 | — | — | EP | disclosed |
| US-4293467-A | POLYPROPYLENE, OXIDATION RESISTANCE | AMERICAN CYANAMID COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| EP-0032566-A1 | Isopropylidenedicyclohexylene esters and their use as light stabilizers | AMERICAN CYANAMID COMPANY (US) | 1981-07-29 | — | — | EP | disclosed |
| US-4237042-A | BY INCORPORATING N-HEXADECYL 3,5-DI-TERT-BUTYL-4-HYDROXYBENZOATE AND A DIALKYL PENTAERYTHRITYL DIPHOSPHITE | AMERICAN CYANAMID COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| EP-0010346-A1 | Polyolefins stabilized against light-induced degradation and a light stabilizer composition therefor | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |