Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216172 | 1.00 | ACE (0.47) | ACEKMT2AABCB11 | |
| SCHEMBL11214777 | 0.89 | ACE (0.50) | ACEKMT2A | |
| SCHEMBL11210147 | 0.89 | ACE (0.50) | ACEKMT2A | |
| SCHEMBL11210318 | 0.83 | ACE (0.50) | ACE | |
| SCHEMBL11210324 | 0.83 | ACE (0.50) | ACE | |
| SCHEMBL11456369 | 0.81 | ACE (0.52) | ACEKMT2A | |
| SCHEMBL11219660 | 0.80 | ACE (0.48) | ACE | |
| SCHEMBL11214998 | 0.79 | ACE (0.42) | ACE | |
| SCHEMBL11221148 | 0.79 | ACE (0.39) | ACE | |
| SCHEMBL11221151 | 0.79 | ACE (0.39) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |