Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 17/20 | 0.73 |
| ▸ | HRH1 | P35367 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121718 | 0.93 | SSTR5 (0.73) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121435 | 0.90 | SSTR5 (0.73) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121477 | 0.87 | SSTR5 (0.72) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121999 | 0.86 | SSTR5 (0.73) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1381246 | 0.85 | SSTR5 (1.00) | SSTR5HRH1HTR2BOPRK1 | |
| SCHEMBL1121254 | 0.84 | SSTR5 (0.73) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121167 | 0.84 | SSTR5 (0.72) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121826 | 0.83 | SSTR5 (0.72) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121682 | 0.83 | SSTR5 (0.79) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1121789 | 0.83 | SSTR5 (0.72) | SSTR5HRH1HTR2BSSTR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-B1 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-02-09 | — | — | EP | claimed |