Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | FDPS | P14324 | 1/20 | 0.61 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 6/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217091 | 1.00 | TTR (0.71) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL2906674 | 0.94 | TTR (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL31408755 | 0.94 | TTR (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4866988 | 0.94 | TTR (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL15927553 | 0.94 | TTR (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6552271 | 0.94 | TTR (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL11815106 | 0.92 | MAOB (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL11815111 | 0.92 | MAOB (0.64) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL11815273 | 0.92 | TTR (0.62) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL11815268 | 0.92 | TTR (0.62) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040177-B1 | PROCESS FOR THE PREPARATION OF BENZENE OR NAPHTHALENE ALKENYL CARBOXYLIC ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |