Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Morpholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL28279707 | 1.00 | MEN1 (0.61) | — | |
| Morpholine SCHEMBL28078522 | 0.97 | MEN1 (0.58) | — | |
| Morpholine SCHEMBL27723090 | 0.97 | MEN1 (0.58) | — | |
| Morpholine SCHEMBL11143962 | 0.97 | MEN1 (0.67) | — | |
| Morpholine SCHEMBL28987277 | 0.97 | MEN1 (0.58) | — | |
| Morpholine SCHEMBL27588949 | 0.89 | KDM4E (0.55) | — | |
| Morpholine SCHEMBL10949531 | 0.88 | MEN1 (0.48) | — | |
| Morpholine SCHEMBL8521651 | 0.88 | MEN1 (0.48) | — | |
| Morpholine SCHEMBL456806 | 0.88 | — | — | |
| Morpholine SCHEMBL11338140 | 0.85 | MEN1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504650-A | Method for preparing morpholine ethanol by using morpholine ethylene oxide method | 四川鸿鹏新材料有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-118105724-A | Reaction device and process for producing dimorpholinodiethyl ether | 安徽恒光聚氨酯材料有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-115029097-B | Easily-extruded double-component polyurethane hollow glass sealant and preparation method thereof | 郑州华普密封材料有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115466231-B | Method for preparing 3- [2- (4-morpholinyl) ethoxy ] propionitrile by pipelining | 浙江大学 | 2024-03-08 | — | — | CN | claimed |
| CN-115557916-A | Process for preparation of morpholinylethyldimethylaminopropyl ether | 南通恒光大聚氨酯材料有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-115466231-A | Method for preparing 3- [2- (4-morpholinyl) ethoxy ] propionitrile by pipelining | 浙江大学 | 2022-12-13 | — | — | CN | claimed |
| CN-115304454-A | Separation method and system for recovering ethylene glycol in polyester production process | 中国石油化工股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115304455-A | Purification method and system for recovering ethylene glycol in polyester production process | 中国石油化工股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-111892902-B | Novel double-component modified polyurethane sealant for hollow glass and preparation method thereof | 郑州大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115029097-A | Easily-extruded double-component polyurethane hollow glass sealant and preparation method thereof | 郑州华普密封材料有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-1974564-B | Preparation process of mycophenolate mofetil | XINBEIJIANG PHARMACEUTICAL CO LTD LIZHU GROUP | 2010-05-12 | — | — | CN | claimed |
| CN-100484930-C | Preparation method of mycophenolate mofetil | CHONGQING DAXIN PHARMACEUTICAL (CN) | 2009-05-06 | — | — | CN | claimed |
| CN-100427475-C | Naproxen-2-aryl morpholine ethyl ester and its preparation method and uses | UNIV SOUTH CHINA TECH (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-101205214-A | Benzimidazole compound for anti-inflammatory and analgesic | UNIV SHENYANG (CN) | 2008-06-25 | — | — | CN | claimed |
| CN-101037427-A | Preparation method of tested and reference mycophenolate mofetil | BEIJING FOUNDER GROUP CO LTD (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-1974564-A | Prepn process of Mycophenolate mofetil | XINBEIJIANG PHARMACEUTICAL CO (CN) | 2007-06-06 | — | — | CN | claimed |
| CN-1970546-A | Naproxen-2-aryl morpholine ethyl ester and its preparation method and uses | UNIV SOUTH CHINA TECH (CN) | 2007-05-30 | — | — | CN | claimed |
| US-6767399-B2 | FLOWABILITY AND HIGH EARLY STRENGTH | THE EUCLID CHEMICAL COMPANY | 2004-07-27 | — | — | US | claimed |
| US-20030167973-A1 | Admixture for producing cementitious compositions having good fluidity and high early compressive strength | BORAL MATERIAL TECHNOLOGIES, INC. | 2003-09-11 | — | — | US | claimed |
| EP-0101093-B1 | DIESEL FUEL COMPOSITION | ETHYL CORPORATION (US) | 1988-01-07 | — | — | EP | claimed |