SCHEMBL11219595

SCHEMBL11219595

CCCCCN1C(=O)c2ccccc2C1=S

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
ALDH2 P05091 1/20 0.58
ALDH3A1 P30838 1/20 0.58
CDC25A P30304 10/20 0.56
CES1 P23141 2/20 0.56
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28080409 0.98 CDC25A (0.59) ALDH1A1ALDH2ALDH3A1CDC25ACES1
SCHEMBL10930457 0.98 CDC25A (0.59) ALDH1A1ALDH2ALDH3A1CDC25ACES1
SCHEMBL2426925 0.98 CDC25A (0.59) ALDH1A1ALDH2ALDH3A1CDC25ACES1
SCHEMBL11455316 0.95 NPC1 (0.53) ALDH1A1ALDH2ALDH3A1CDC25ACES1
Urea SCHEMBL28145517 0.91 CDC25A (0.53) ALDH1A1ALDH2ALDH3A1CDC25ACES1
SCHEMBL11840055 0.91 TDP1 (0.56) TDP1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL11622377 0.90 TDP1 (0.59) TDP1L3MBTL1SMN1; SMN2
SCHEMBL11832457 0.90 TDP1 (0.59) TDP1L3MBTL1SMN1; SMN2
SCHEMBL11841498 0.90 TDP1 (0.59) TDP1L3MBTL1SMN1; SMN2
SCHEMBL11838939 0.90 TDP1 (0.59) TDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4409018-A HERBICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1983-10-11 US disclosed
EP-0041256-A1 Hexahydroisoindol derivatives, process for producing said compounds and herbicides containing said compounds Takeda Chemical Industries, Ltd. (JP) 1981-12-09 EP disclosed