SCHEMBL11220260

SCHEMBL11220260

COC(=O)CC1CCC(=O)C1CC#CCCO

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AKR1C4 P17516 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
BRD4 O60885 1/20 0.34
PTGER3 P43115 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11798100 0.86 AKR1C4 (0.41) AKR1C4AKR1C3AKR1C2BRD4PTGER3
SCHEMBL29634374 0.86 AKR1C4 (0.41) AKR1C4AKR1C3AKR1C2BRD4PTGER3
SCHEMBL13388528 0.80 PTGER3 (0.41) AKR1C4AKR1C3AKR1C2PTGER3
SCHEMBL12213277 0.80 PTGER3 (0.41) AKR1C4AKR1C3AKR1C2PTGER3
Ethylene Glycol SCHEMBL23923598 0.75 PTGER2 (0.42) AKR1C4AKR1C3AKR1C2PTGER3
Ethylene Glycol SCHEMBL22125447 0.75 PTGER2 (0.42) AKR1C4AKR1C3AKR1C2PTGER3
SCHEMBL11514658 0.75 AKR1C4 (0.48) AKR1C4AKR1C3AKR1C2BRD4PTGER3
SCHEMBL2477633 0.75 AKR1C4 (0.51) AKR1C4AKR1C3AKR1C2BRD4PTGER3
SCHEMBL2477632 0.75 AKR1C4 (0.51) AKR1C4AKR1C3AKR1C2BRD4PTGER3
SCHEMBL11107741 0.74 PTGER3 (0.46) PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57031641-A None JP disclosed
JP-S5731641-A 5'-HYDROXYJASMONIC ACID DERIVATIVE, ITS PREPARATION, AND ITS INTERMEDIATE T HASEGAWA CO LTD 1982-02-20 JP disclosed